Case History

The following clinical cases are examples of how GlucoDay S may be used to detect problems often encountered in the management of diabetic patients

Case History: case 1 - case 2 - case 3 - case 4

CLINICAL CASE 1

This graph shows the first 24 hours of continuous glucose monitoring in a DM1 patient with hypoglycaemia unawareness. As can be seen, prolonged asymptomatic hypoglycaemia (for more than 150 minutes) during the night was detected by the GlucoDay®. Only when the patient woke up to check his blood glucose at 3am (as planned by the protocol) did he find himself to be hypoglycaemic.

M.L. 52 yrs, DM1, HbA1c=7.4% Duration 25 yrs, Hypo unawareness

The day after, with a slight modification in the NPH dosage and a bedtime snack, we were able to avoid the hypoglycaemia during the night as shown in this graph:

Venous blood glucose measurements are represented in red whilst capillary blood glucose measurements are represented in yellow.

M.L. 52 yrs, DM1, HbA1c=7.4% Duration 25 yrs, Hypo unawareness

Clinical study granted by Dr. Alberto Maran, Dept. of Clinical and Experimental Medicine, University of Padua, Italy.

CLINICAL CASE 2

In this young diabetic patient a prolonged hypoglycaemia episode was recorded after insertion of the microdialysis probe despite the fact that he tried to correct the episode with ingestion of sugar after he realised he was hypo. However it was only after 6 hours and ingestion of a large amount of carbohydrates that he recovered from hypoglycaemia with a subsequent hyperglycaemia before supper.

M.C. (M) age19, DM1, HbA1c=7.8% Duration 16 yrs

Day 1

In the next 24 hours no hypoglycaemia was detected, however, as shown in this graph, in the late morning during a party in his classroom, he tried to correct hyperglycaemia with two extra injections of short acting insulin and this was recorded by the GlucoDay. Venous blood glucose measurements are represented in red whilst capillary blood glucose measurements are represented in yellow. M.C. (M) age19, DM1, HbA1c=7.8% Duration 16 yrs

Day 2

Clinical study granted by Dr. Alberto Maran, Dept. of Clinical and Experimental Medicine, University of Padua, Italy.

CLINICAL CASE 3

3 Post-prandial hypoglycaemia episodes (after lunch, supper and breakfast) were detected in this young diabetic patient as you can see in this profile. Venous blood glucose measurements are represented in red whilst capillary blood glucose measurements are represented in yellow.

P.E. (F) age 23, DM1, HbA1c=8.7% Duration 21 yrs

Clinical study granted by Dr. Alberto Maran, Dept. of Clinical and Experimental Medicine, University of Padua, Italy.

CLINICAL CASE 4

In this DM1 diabetic patient a prolonged hypoglycaemia episode during the night was detected by the GlucoDay®.

S.M. (F) age 60, DM1, HbA1c=7.5% Duration 44 yrs

Day 1

Modification of the insulin profile was able to avoid hypoglycaemia the subsequent night. Venous blood glucose measurements are represented in red whilst capillary blood glucose measurements are represented in yellow. S.M. (F) age 60, DM1, HbA1c=7.5% Duration 44 yrs

Day 2

Clinical study granted by Dr. Alberto Maran, Dept. of Clinical and Experimental Medicine, University of Padua, Italy.

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